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Typical specifics of the Risk-free and successful utilization of Depakote Medicines are sometimes prescribed for purposes besides Those people shown within a Medication Guide. Will not use Depakote for just a issue for which it was not prescribed.
are allergic to divalproex sodium, valproic acid, sodium valproate, or any of the components in Depakote. Begin to see the stop of the Medication Manual for an entire listing of substances in Depakote.
Whilst there won't be any efficacy information that precisely handle more time-term antimanic treatment with Depakote, the security of Depakote in extended-phrase use is supported by info from file evaluations involving somewhere around 360 clients dealt with with Depakote for larger than three months.
Based upon two placebo-managed medical trials and their long lasting extension, valproate was frequently properly tolerated with most adverse reactions rated as gentle to reasonable in severity. In the 202 individuals subjected to valproate within the placebo-managed trials, seventeen% discontinued for intolerance.
Valproate is for that reason contraindicated for prophylaxis of migraine problems in Expecting Ladies and in Women of all ages of childbearing possible that are not making use of productive contraception [see Contraindications (4)].
Depakote is usually indicated for use as sole and adjunctive therapy while in the procedure of simple and complex absence seizures, and adjunctively in patients with many seizure sorts that include absence seizures.
Pertaining to breastfeeding, caution is advised considering the fact that valproate does pass into breast milk in tiny quantities.
Prescribers should really observe serum valproate concentrations and medical response when adding or discontinuing estrogen made up of products and solutions.
All Females of childbearing age (including women from the beginning of puberty) ought to communicate to their Health care supplier about employing other doable treatment plans rather than Depakote. If the decision is manufactured to implement Depakote, it is best click here to use helpful delivery Command (contraception).
All other medications you are currently having (which include in excess of the counter solutions, herbal and nutritional health supplements) and any medication allergies you have
Lower platelets. Platelets support the blood to clot. Bruising much easier than ordinary is really a symptom of lower platelets
People today residing with bipolar problem who wish to be pregnant facial area critical decisions. It can be crucial to debate the dangers and great things about remedy with your doctor and caregivers.